An increase in serum creatinine of ≥0.5 % mg/dL after indomethacin was observed in about 10-15 % of the patients and creatinine returns to a normal level about 1 week after cessation of therapy. Painful, Red Or Swollen Mouth 7. Indomethacin prescription and dosage sizes information for physicians and healthcare professionals. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Indomethacin is also used to treat pain in the shoulder caused by bursitis (inflammation of a fluid-filled sac in the shoulder joint) and tendinitis (inflammation of the tissue that connects muscle to bone)… Check with your doctor immediately if any of the following side effects occur: Get emergency help immediately if any of the following symptoms of overdose occur: Some side effects may occur that usually do not need medical attention. Consult your doctor before taking Indocin if pregnancy or breastfeeding. Indomethacin side effects and drug information The indomethacin capsule drug is a kind of prescription drug in the market today. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer — Mayo Clinic Health Letter, Time running out - 40% off Online Mayo Clinic Diet ends soon. Generally, indomethacin is used to address the symptoms of swelling and joint pain in osteoarthritis or rheumatoid arthritis. These side effects may go away during treatment as your body adjusts to the medicine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. It is similar to ibuprofen and naproxen (Naprosyn, Aleve).Indomethacin works by reducing the production of prostaglandins. This site complies with the HONcode standard for trustworthy health information: verify here. Merck & Co, Inc, West Point, PA. 3. What are the possible side effects of indomethacin (Indocin, Indocin SR, Tivorbex)? See below for a comprehensive list of adverse effects. What does this mean? Description and Brand Names; Before Using; Proper Use; Precautions; Side Effects; Products and services. Excessive Sweating 5. Side effects are reported by people who take Indomethacin. This effect may be lessened by taking indomethacin with food or by taking an antacid. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Can I take Tylenol while taking indomethacin and can these drugs be alternated every 3 hours? Indomethacin 25 mg Tablet is used for the treatment of pain, swelling, and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, gout, and ankylosing spondylitis. Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at a greater risk for serious GI events. Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in … [Ref], Uncommon (0.1% to 1%): Toxic hepatitis, jaundice, elevated ALT/AST, Frequency not reported: Cholestasis, abnormal liver function[Ref], In controlled clinical trials, renal dysfunction occurred statistically significantly more frequently during IV use in neonates than in those treated with placebo. Commonly reported side effects of indomethacin include: headache. Furthermore, the medication may cause diarrhea or constipation together with abdominal pain. Indomethacin is a nonsteroidal anti-inflammatory drug that reduces fever, pain and inflammation. Advertising revenue supports our not-for-profit mission. Indomethacin may aggravate these conditions. Loss Of Appetite 6. 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